Chemical Structure : [Ipilimumab
CAS No.: 477202-00-9
货号: PC-Ab1018Not For Human Use, Lab Use Only.
Ipilimumab is a fully human IgG1κ antibody that binds to CTLA-4 (cytotoxic T lymphocyte-associated antigen 4), a molecule on T-cells that is indicated for unresectable or metastatic melanoma. The absence or presence of CTLA-4 can augment or suppress the immune system’s T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells. The proposed mechanism of action is indirect, and may be thro
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
大包装,大折扣!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Ipilimumab is a fully human IgG1κ antibody that binds to CTLA-4 (cytotoxic T lymphocyte-associated antigen 4), a molecule on T-cells that is indicated for unresectable or metastatic melanoma. The absence or presence of CTLA-4 can augment or suppress the immune system’s T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells. The proposed mechanism of action is indirect, and may be through T-cell – mediated anti-tumor immune responses.
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
|
Chemical Name/SMILES |
Ipilimumab; Yervoy; MDX-010; BMS-73401; cytotoxic T-lymphocyte-associated protein 4;CTLA-4 protein; CD152; 477202-00-9; cytotoxic T-lymphocyte antigen 4 |
1. 1, Wolchok JD, et al. Lancet Oncol. 2010 Feb;11(2):155-64. 2, Bashey A, et al. Blood. 2009 Feb 12;113(7):1581-8. 3, Yang JC, et al. J Immunother. 2007 Nov-Dec;30(8):825-30. 4, O'Day SJ, et al. Cancer. 2007 Dec 15;110(12):2614-27.
备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright